Video games/P

Pa

 * Parodius: A video game franchise based on Gradius with quirky elements and GTS thematic.

Pe

 * Persona 5: Even though Milady is only visible through her dress and mask, she is still considered a mini-giantess.

Po

 * Pokémon: A franchise where a trainer must catch monsters called "Pokémon", train them and send them to fight with other Pokémon.

Pr

 * Prinny 2: Dawn of Operation Panties, Dood!: A spin-off video game of the Disgaea saga. The main character is the penguin butler of Etna. There are 2 notable giantesses: Joshua the Omega Ice Elemental (who is constantly ignoring the battle and fighting with indirect attacks); and Etna, the secret and final boss of the game.