Western animation/D

Da

 * Dan Vs. - SE3-EP03: Dan will try to take revenge on his new boss. After it is revealed that the leader of the protagonists turned out to be a demon and after Dan throws holy water on her, the boss becomes enraged and grows in size, looking more corpulent and threatening.
 * Danny Phantom - SE?-EP??:
 * Darkwing Duck - SE1-EP04: “Getting Antsy”. Darkwing Duck gets shrunk smaller than a ant and in a short scene, Gosalyn Mallard appears as a para-giantess who nearly squashes him but steps on his cape. He then fails to get her attention.
 * Dawn of the Croods - SE4-EP02a: Eep cheats on her parents to go to an adult party. When Eep's brother, Tonk, believes that his older sister grew a foot in a day, she predicts that she will become a giantess after a whole season, imagining her terrifying all the cavemen while she is in her hands.

DC

 * DC Super Hero Girls: At Super Hero High School, well-known DC heroes, both male and female, attend challenging classes and deal with all the awkwardness of growing up with the added stress of having unique superpowers.

De

 * Denver, the Last Dinosaur - SE2-EP19: "Denver and the Cornstalk". An embellished version of Jack and the Beanstalk showing Bertha Bird as the evil giantess.
 * Dexter's Laboratory: This series, due to it's fantasy, has had abundant GTS scenes. It has 11 episodes with relative giantess theme.

Di

 * Dinosaucers - EP09:
 * Disenchantment: A magical and medieval fantasy series created by Matt Groening.
 * Disney's House of Mouse - SE3-EP10: Briefly, Alice, the main character of Alice in Wonderland (Disney), appears as giantess.

Do

 * Dofus: The Treasures of Kerub: An animated series based on a video game with the same name.

Dr

 * Dragon Tales: An fantasy preschool animated series about the adventures of 2 children and friendly speaking dragons.

Du

 * DuckTales (1987) - SE3-EP16: "Attack of the Fifty-Foot Webby". An accident in the jungle causes Webby Vanderquack to turn into a giant duck.