Mysterious Joker

Mysterious Joker is a Japanese manga/anime series written and illustrated by Hideyasu Takahashi.

Synopsis
In the story, there is nothing in the world that the mysterious phantom thief Joker cannot steal. He goes after one treasure after another in unpredictable capers with seemingly miraculous tricks.
 * Source: https://myanimelist.net/anime/24909/Kaitou_Joker

Featured relative giantess: Queen Diamond

 * 1) She is a main character.
 * 2) In Mysterious Joker - SE2-EP02, she becomes an inflated imperfect giantess, due she ate too much food.
 * 3) In Mysterious Joker - SE3-EP12, she becomes a para-giantess and interacts with her shrunken friends and rivals.
 * 4) In Mysterious Joker - SE4-EP09, she briefly becomes a para-giantess again.

Featured natural muscular imperfect giantess: Commando Satsuko

 * 1) She is normally a normal sized woman called Kaneko.
 * 2) She can naturally metamorphose into a muscular imperfect giantess called Commando Satsuko.
 * 3) Commando Satsuko appears in Mysterious Joker - SE3-EP04 (debut), Mysterious Joker - SE4-EP05 and Mysterious Joker - SE4-EP08 (last appearance).