Video games/The

L

 * The Legend of Zelda: The Great Fairy is a very prominent giantess throughout the games (franchise).

S

 * The Simpsons: Bart & the Beanstalk: From The Simpsons franchise. A platform game inspired by Jack and the Magic Beans. During Bart's adventure (who plays Jack), he meets the "Giant's wife" (played by Marge Simpson). This GTS scene is just a simple frame (static image).